He & She MD review
Publishes the whole ladder
The advertised $149 needs a twelve-month commitment. Month to month it is $229 — and to their credit, the page prints every rung of that ladder instead of just the bottom one.
Our verdict
He & She MD does something most of this category avoids: it publishes the whole price ladder. Twelve months is $149 a month, six is $159, three is $179, and one month is $229. The headline quotes the cheapest rung, which is normal here, but the page shows you the rest rather than hiding it behind a checkout. So the $80 gap between the advertised rate and the uncommitted one is visible before you pay, and that is worth something. No milligram figure appears anywhere, which is the real omission.
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At a glance
- Category
- NAD⁺ nasal spray
- Format
- Nasal spray
- From
- $229/mo
- Dose published
- No
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Pharmacy
- Not named
- Updated
- September 2026
What it is
A prescription NAD⁺ nasal spray from a telehealth brand that also runs hormone, hair, weight and sexual-health lines. The spray is sold as a plan with a length you pick, and the length is what sets the monthly price.
How it works
Online throughout, with clinician oversight and dose adjustments offered if needed. The site states no membership fee, no insurance requirement and 24/7 support. HSA and FSA are accepted. A $25 discount on a first treatment is offered when you leave the page, which is a capture rather than a standing price.
Pricing transparency
Publishing every rung of a price ladder is rare in this category, and this one rewards reading. Twelve months is $149 a month. Six months is $159. Three months is $179. A single month is $229. The advertised figure is the twelve-month one, so the number you see first assumes you commit for a year — and a year at $149 is $1,788 paid against a service you cannot yet judge. Month to month costs 54% more per month, which is the real price of keeping your options open. What no rung tells you is the amount: the spray's strength is never published, so none of these figures can be turned into a cost per milligram. "Same price at every dose" is stated, which means the amount does not change what you pay, and still leaves you not knowing what the amount is.
Branded vs compounded
Compounded prescription NAD⁺, so it is not FDA-approved and the FDA does not review it for safety, efficacy or quality before dispensing. The compounding pharmacy is not named. The page carries a disclaimer that the product is not intended to diagnose, treat, cure or prevent any disease, which is the right disclaimer to carry.
Pros and watch-outs
What we like
- Publishes every rung of the price ladder, not only the cheapest
- Month-to-month is available rather than commitment-only
- No membership fee on top of the plan price
- HSA and FSA accepted, 24/7 support stated
- Dose adjustments offered under clinician oversight
Watch-outs
- The advertised $149 requires a twelve-month commitment
- Month to month is $229, which is 54% more per month
- No milligram strength published, so no cost per milligram exists
- The compounding pharmacy is not named
- Nasal NAD⁺ has no controlled outcome trial behind it
Best for
Someone who wants a nasal spray and is willing to read a price ladder before choosing a term.
Who should look elsewhere
Anyone who would judge it on the advertised figure, which is a year's commitment, or who needs a strength to compare.
How He & She MD compares
A few alternatives worth a look, depending on what you’re optimizing for.
- Eden
Knowing the vial size and the real ongoing price
See Eden → - RNK Health
Choosing needle or spray without a price penalty
See RNK Health → - System Labs
Knowing exactly how many milligrams you get
See System Labs →
More NAD⁺ nasal spray sellers reviews: WeightCareRCMC Medical CenterWispGentle PatchesMondaeRxPepsDirect
Cost & access · Reviewed and last verified September 2026
How we assessed this. This review reflects NAD Picks’s own read of He & She MD’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- Why is the advertised price $149 when I was quoted $229?
- Because $149 is the twelve-month rate. The published ladder runs $149 a month on twelve months, $159 on six, $179 on three and $229 for a single month. Both numbers are real; they are prices for different commitments, and the one advertised is the one that needs a year.
- How many milligrams are in the spray?
- The page does not say, and "same price at every dose" confirms the amount does not change the price without ever telling you what the amount is. Without a strength there is no cost per milligram, so this cannot be compared against a seller who publishes one.
- Is there a membership fee on top?
- No. The site states there is no membership fee and no insurance requirement, so the monthly figure for your chosen term is what you pay. HSA and FSA are accepted, which may reduce the effective cost depending on your plan.
- Is He & She MD expensive compared with other NAD⁺ nasal spray sellers providers?
- He & She MD publishes a starting figure of $229/mo. Across the 129 NAD⁺ nasal spray sellers providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $170, which puts He & She MD above the median. The other 37 NAD⁺ nasal spray sellers providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.