How much does Immortals NAD⁺ cost?

Injections are shown at $119 a month and the nasal spray at $101, but both are billed quarterly on a three-month commitment paid up front — about $357 and $303 respectively. The struck-through prices of $175 and $140 are labeled as regular rates rather than offered as monthly plans, so there is no month-to-month price you can actually buy.

How much NAD⁺ is in a dose?

Immortals publishes a titration — ten units three times a week in the first week, increasing by ten units weekly to a maximum of fifty — but no concentration. Units measure the volume on an insulin syringe, not the drug, so without knowing the milligrams per milliliter there is no way to turn fifty units into a quantity. Publishing a schedule is better than publishing nothing; it still does not make the price comparable.

Are the studies on the page real?

Yes, and we checked them against PubMed on September 13, 2026. The 2022 paper by Yang and colleagues in Frontiers in Endocrinology exists, and measured whole-blood NAD⁺ in 1,518 people. It reports that men aged sixty and over sat about 2 micromoles per liter below men under thirty, while women showed no significant change across age groups. Which is what the page says. The 2012 paper by Massudi and colleagues in PLoS ONE also exists and also found NAD⁺ falling with age.

So does NAD⁺ really fall 87% with age?

That figure needs its context, and the page does not give it. It traces to the Massudi study, which measured NAD⁺ in pelvic skin samples from 49 people — a small tissue-specific sample, not whole-body levels. The larger blood study the same page cites found a mean of about 33 micromoles per liter with roughly a 2-unit gap in older men, which is a difference of single-digit percent, not 87. Both papers are real; they are measuring different things, and only one of them supports a dramatic number.

Do their two sources agree about women?

No, and it is worth noticing that the page prints both. The blood study concludes that NAD⁺ decline with age was observed only in men, with no significant difference across age groups in women. The skin study found a significant negative correlation between NAD⁺ and age in women as well as men. A seller putting both on the same page is being more transparent than most; a reader should take from it that the underlying science is less settled than the headline suggests.

Updated September 2026

Immortals review

Cites sources, sells commitment

Cites named studies on the product page, with authors and journals — and will not sell you a single month.

Our verdict

Immortals does something almost nobody else in this category does: it names its sources, with authors, journals and years, and one of them it summarizes accurately. That is worth a lot. What it will not give you is a month-to-month price. The $119 a month for injections is billed quarterly on a three-month commitment paid up front, roughly $357 before your first shot, and the only other number on the page is a struck-through $175 that is not offered as a plan. If you want to try one month, this is not the service that sells it.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

Check availability →

At a glance

Category: NAD⁺ injections
Format: Injection · Nasal spray
Dose published: No
Prescription: Required
Compounded: Yes — not FDA-approved
Pharmacy: Not named
Updated: September 2026

What it is

The medical arm of Bryan Johnson's longevity business, selling compounded NAD⁺ in two formats — subcutaneous injection and nasal spray — inside a wide prescription catalog that runs from GLP-1s and branded weight-loss drugs to tadalafil, metformin, tretinoin, hair and skin complexes and biomarker testing. The proposition is explicitly that you are buying the prescribing framework used by Johnson's own medical team.

How it works

A guided medical intake covering history, current medications and goals, reviewed by a US-licensed, board-certified physician within seventy-two hours, who recommends a medication if appropriate; some states require a live audio or video consultation first. Approved medications ship in two to five business days from licensed US pharmacies. There are no membership fees, no insurance, and unlimited messaging with the doctor for up to twelve months, with video consults available. Plans are stated to be HSA and FSA reimbursable.

Pricing transparency

Injections are listed at $119 a month against a struck-through $175, and the nasal spray at $101 against $140. The footnote under the price does the real work: the lower figure is billed quarterly with a three-month commitment paid up front, which is about $357 for injections or $303 for the spray before your first dose. No month-to-month plan appears anywhere on the page, and the $175 is presented as a regular price rather than a purchasable option, so there is no standing monthly rate to quote. On a per-month basis $119 sits below System Labs at $149 and Breeze Meds at $169; you simply cannot buy it a month at a time.

Branded vs compounded

Compounded NAD⁺. The disclaimer under the research charts states that compounded medications are not evaluated by the FDA for safety, quality or efficacy, which is correct and correctly placed — compounded drugs are made by a licensed pharmacy against an individual prescription and never reach FDA review before dispensing. Dosing is published, but in insulin units rather than milligrams: ten units three times a week for the first week, rising by ten units weekly to a maximum of fifty. Without a stated concentration, units do not convert into a quantity, so the price still cannot be compared per milligram. The pharmacies are described as licensed and US-based but are not named.

Pros and watch-outs

What we like

Cites named studies with authors, journals and years on the product page — almost unheard of in this category
The prepaid injection rate works out to $119 a month, below System Labs at $149
Nasal spray offered as an alternative format at a lower price than the injection
No membership fee, and unlimited physician messaging for up to twelve months
Publishes a titration schedule rather than leaving dosing entirely unstated
Warns that people with a history of or susceptibility to cancer should use NAD⁺ with caution — a safety note most competitors omit
States that compounded medications are not evaluated by the FDA

Watch-outs

No month-to-month option: the advertised rate requires three months paid up front
The struck-through $175 a month is not offered as a plan you can actually buy
Dosing is given in insulin units with no concentration, so no milligram figure can be derived
The headline 87% decline figure comes from skin tissue in 49 people, which the page does not mention
Two of its own cited papers disagree about whether women's NAD⁺ declines with age, and the page presents both
The pharmacies are not named

Best for

A reader who wants sources on the page and a physician-led framework behind the prescription, and who is committing to a quarter rather than testing a month.

Who should look elsewhere

Anyone who wants to try NAD⁺ for one month before deciding. Every option here is a three-month prepayment, and the alternative price shown is not a plan you can select.

How Immortals compares

A few alternatives worth a look, depending on what you’re optimizing for.

Eden
Knowing the vial size and the real ongoing price
See Eden →
RNK Health
Choosing needle or spray without a price penalty
See RNK Health →
System Labs
Knowing exactly how many milligrams you get
See System Labs →

Compare all providers side by side →

More NAD⁺ injection providers reviews: PreventiveMDSprout HealthYourHealthRxNeo Soma HealthcareRylo HealthVytora Health

Laura Bennett

Evidence & trials · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Immortals’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does Immortals NAD⁺ cost?: Injections are shown at $119 a month and the nasal spray at $101, but both are billed quarterly on a three-month commitment paid up front — about $357 and $303 respectively. The struck-through prices of $175 and $140 are labeled as regular rates rather than offered as monthly plans, so there is no month-to-month price you can actually buy.
How much NAD⁺ is in a dose?: Immortals publishes a titration — ten units three times a week in the first week, increasing by ten units weekly to a maximum of fifty — but no concentration. Units measure the volume on an insulin syringe, not the drug, so without knowing the milligrams per milliliter there is no way to turn fifty units into a quantity. Publishing a schedule is better than publishing nothing; it still does not make the price comparable.
Are the studies on the page real?: Yes, and we checked them against PubMed on September 13, 2026. The 2022 paper by Yang and colleagues in Frontiers in Endocrinology exists, and measured whole-blood NAD⁺ in 1,518 people. It reports that men aged sixty and over sat about 2 micromoles per liter below men under thirty, while women showed no significant change across age groups. Which is what the page says. The 2012 paper by Massudi and colleagues in PLoS ONE also exists and also found NAD⁺ falling with age.
So does NAD⁺ really fall 87% with age?: That figure needs its context, and the page does not give it. It traces to the Massudi study, which measured NAD⁺ in pelvic skin samples from 49 people — a small tissue-specific sample, not whole-body levels. The larger blood study the same page cites found a mean of about 33 micromoles per liter with roughly a 2-unit gap in older men, which is a difference of single-digit percent, not 87. Both papers are real; they are measuring different things, and only one of them supports a dramatic number.
Do their two sources agree about women?: No, and it is worth noticing that the page prints both. The blood study concludes that NAD⁺ decline with age was observed only in men, with no significant difference across age groups in women. The skin study found a significant negative correlation between NAD⁺ and age in women as well as men. A seller putting both on the same page is being more transparent than most; a reader should take from it that the underlying science is less settled than the headline suggests.

Check availability →

Or compare every NAD⁺ injection provider.