How much does NAD+ Cell Regenerator cost?

$40.50 for 30 vegetarian capsules at 300 mg each, which is a month at the stated one-a-day serving. Setting up AutoShip brings it to $36.00. A lower-strength 100 mg version of the same product is sold separately at a lower price, so check the strength before you order.

Is the 51% NAD+ increase claim accurate?

Yes, and that is not something we get to say often here. The trial is a 2019 randomized, double-blind, placebo-controlled study of NIAGEN nicotinamide riboside in healthy overweight adults, and it found that 100, 300 and 1000 mg raised whole blood NAD⁺ by 22%, 51% and 142% within two weeks. Life Extension quotes the 300 mg arm, which is the dose in this capsule, at the right timepoint. The caveat is who ran it: ChromaDex, the company that makes NIAGEN, funded the trial and two of the three authors worked for it.

How is this different from Tru Niagen?

It is the same ingredient at the same dose from the same supplier. ChromaDex makes NIAGEN and sells it under its own Tru Niagen brand while also licensing it to other companies, Life Extension among them. The practical difference is price and packaging: 300 mg costs $40.50 here as a one-time purchase against $49.00 from Tru Niagen, though Tru Niagen's subscription rate undercuts both.

Will it give me more energy?

There is no controlled human trial showing that NAD⁺ supplementation increases energy in healthy people, for this product or any other. What the trials establish is that nicotinamide riboside raises measured blood NAD⁺ at the doses on this label. Life Extension's page mostly stays on the right side of that line, which is more than most of this category manages.

Do I need the 300 mg version rather than the 100 mg one?

The 300 mg dose is the one the trial evidence sits on most directly — it is the arm that produced the 51% figure, and the 100 mg arm produced 22%. If you are buying nicotinamide riboside at all, buying the dose that was actually studied costs a few dollars more and removes the guesswork.

Is Life Extension NAD+ Cell Regenerator expensive compared with other NAD⁺ precursor supplements providers?

Life Extension NAD+ Cell Regenerator publishes a starting figure of $40.5/mo. Across the 116 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Life Extension NAD+ Cell Regenerator below the median, toward the cheaper end. The other 33 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Life Extension NAD+ Cell Regenerator review

Quotes its trial correctly

One ingredient, one dose, one correctly quoted trial — and the lowest standing price we can find for 300 mg of NIAGEN.

Our verdict

There is nothing exciting here, and that is the point. A single capsule holds 300 mg of NIAGEN nicotinamide riboside and nothing else worth naming, the price is $40.50 for thirty days, and the one clinical claim on the page is quoted accurately from a real trial — which, in this category, is close to remarkable. What it does not do is promise you anything the evidence cannot support. Raising NAD⁺ is what nicotinamide riboside is proven to do, and raising NAD⁺ is all Life Extension says it does.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

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At a glance

Category: NAD⁺ supplement
Format: Oral precursor
From: $40.50
Dose published: Yes
Prescription: Not required
Compounded: No
Updated: September 2026

What it is

A one-a-day capsule containing 300 mg of NIAGEN nicotinamide riboside chloride, the trademarked NR ingredient used in most of the published human research on this molecule. No stack, no proprietary blend. Life Extension also sells a 100 mg version at a lower price.

How it works

Retail, not telehealth. There is no intake, no prescriber and no clinician attached — you buy a supplement and take it. Life Extension has its own AutoShip program and rewards tier, neither of which changes what is in the capsule.

Pricing transparency

$40.50 for 30 capsules — a month at one a day — with an AutoShip price of $36.00 if you set up recurring delivery. We quote the standing rate. The dose is printed on the page in a proper Supplement Facts panel: 300 mg of NIAGEN nicotinamide riboside chloride per capsule, with only microcrystalline cellulose, silica and the vegetable capsule alongside it. That is the same trademarked ingredient at the same daily amount that Tru Niagen sells for $49.00 as a one-time purchase, which makes this the cheaper way to buy identical milligrams if you are not subscribing.

Branded vs compounded

A dietary supplement, not a drug. It is not FDA-approved, and the FDA does not review supplements for safety or efficacy before sale — Life Extension prints that disclaimer on the product page. The 51% figure it quotes comes from a real randomized, placebo-controlled trial of NIAGEN, and is quoted correctly, including the 300 mg dose and the two-week timepoint. Worth knowing about that trial: it was funded by ChromaDex, which makes NIAGEN, two of its three authors were ChromaDex employees, and the third is the company's chief scientific adviser. That does not make the number wrong, and you should be told rather than left to find out.

Pros and watch-outs

What we like

300 mg of NIAGEN nicotinamide riboside, stated in a full Supplement Facts panel
Cheaper per month than any other 300 mg NIAGEN product we can verify
The single clinical claim on the page is quoted accurately from the trial it cites
One ingredient — no proprietary blend, no caffeine, no niacin load
No prescription, no intake, no subscription to a telehealth service

Watch-outs

Raising NAD⁺ is proven; the healthy-aging outcomes the category is sold on are not
A supplement, so no FDA review of safety or efficacy before sale
The trial behind the headline number was funded and largely authored by the ingredient's manufacturer
No clinician involved — nobody is assessing whether it suits you
The page sells a 100 mg version alongside it, which is easy to buy by mistake

Best for

Anyone who has decided to try nicotinamide riboside and wants the studied dose at the lowest price, without paying for a stack of extras that have not been tested together.

Who should look elsewhere

Someone looking for a formula that has been trialed as a formula, or who wants a company that has run research of its own. This is a well-made commodity capsule, and it is priced like one.

How Life Extension NAD+ Cell Regenerator compares

A few alternatives worth a look, depending on what you’re optimizing for.

Care Bare Rx
Anyone who wants the price up front
See Care Bare Rx →
Breeze Meds
The lowest listed injection price
See Breeze Meds →
CoreAge Rx
The lowest published NAD⁺ price
See CoreAge Rx →

Compare all providers side by side →

More NAD⁺ precursor supplements reviews: Bloom MDLevers HealthAquaVita NextGenNäkyFierce HealthARSYNL Rx

Michael Reyes

Cost & access · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Life Extension NAD+ Cell Regenerator’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does NAD+ Cell Regenerator cost?: $40.50 for 30 vegetarian capsules at 300 mg each, which is a month at the stated one-a-day serving. Setting up AutoShip brings it to $36.00. A lower-strength 100 mg version of the same product is sold separately at a lower price, so check the strength before you order.
Is the 51% NAD+ increase claim accurate?: Yes, and that is not something we get to say often here. The trial is a 2019 randomized, double-blind, placebo-controlled study of NIAGEN nicotinamide riboside in healthy overweight adults, and it found that 100, 300 and 1000 mg raised whole blood NAD⁺ by 22%, 51% and 142% within two weeks. Life Extension quotes the 300 mg arm, which is the dose in this capsule, at the right timepoint. The caveat is who ran it: ChromaDex, the company that makes NIAGEN, funded the trial and two of the three authors worked for it.
How is this different from Tru Niagen?: It is the same ingredient at the same dose from the same supplier. ChromaDex makes NIAGEN and sells it under its own Tru Niagen brand while also licensing it to other companies, Life Extension among them. The practical difference is price and packaging: 300 mg costs $40.50 here as a one-time purchase against $49.00 from Tru Niagen, though Tru Niagen's subscription rate undercuts both.
Will it give me more energy?: There is no controlled human trial showing that NAD⁺ supplementation increases energy in healthy people, for this product or any other. What the trials establish is that nicotinamide riboside raises measured blood NAD⁺ at the doses on this label. Life Extension's page mostly stays on the right side of that line, which is more than most of this category manages.
Do I need the 300 mg version rather than the 100 mg one?: The 300 mg dose is the one the trial evidence sits on most directly — it is the arm that produced the 51% figure, and the 100 mg arm produced 22%. If you are buying nicotinamide riboside at all, buying the dose that was actually studied costs a few dollars more and removes the guesswork.
Is Life Extension NAD+ Cell Regenerator expensive compared with other NAD⁺ precursor supplements providers?: Life Extension NAD+ Cell Regenerator publishes a starting figure of $40.5/mo. Across the 116 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Life Extension NAD+ Cell Regenerator below the median, toward the cheaper end. The other 33 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every NAD⁺ supplement.