How much does Qualia NAD+ cost?

$79.00 for a 56-capsule container, a 28-day supply at two capsules a day, bought outright. On subscription the first shipment is $29.00 and every shipment after that is $69.00, billed every four weeks.

Is the 67% NAD+ increase real?

It comes from Qualia's own second placebo-controlled study, in which 63 participants were analyzed and blood NAD⁺ rose 67% against 4% on placebo. That study is a preprint, not a peer-reviewed paper, and Qualia says so on the page itself. It is also worth seeing the shape of the recruitment: 170 people were enrolled, 102 returned a usable baseline sample, and 63 returned both samples. A company disclosing that attrition in its own marketing write-up is doing something unusual and good, but a 67% figure drawn from 63 self-collected finger-stick samples is a preliminary result, not a settled one.

Will it make me feel better?

The two studies disagree on that, in a revealing way. In the first, men reported improvement on an aging-symptoms scale and women did not. In the second, women improved on the same kind of scale and men showed nothing significant. Qualia's own study page adds that the trial had limited power to detect differences on those secondary measures and that they should be read cautiously. Take that at face value: the NAD⁺ increase is the finding, and the feel-better results are not yet a result.

What is in it besides nicotinamide riboside?

Per two-capsule serving: 300 mg NIAGEN nicotinamide riboside, 254 mg of niacin equivalents from niacinamide and niacin, 50 mg trans-resveratrol, 150 mg of a marine trace mineral blend, 50 mg magnesium, and 40 mg of whole coffee fruit extract supplying 28 mg of caffeine. Then small amounts of thiamine, riboflavin, B6, folate, B12, biotin and pantothenic acid.

Can it cause flushing?

Qualia says it can. The formula contains nicotinic acid, the form of vitamin B3 that causes flushing at doses well above the daily value. The company states on the product page that the amount is below the level at which flushing usually occurs, but that the possibility cannot be ruled out — particularly on an empty stomach. The niacinamide and nicotinamide riboside in the formula do not cause it.

Is Qualia NAD+ expensive compared with other NAD⁺ precursor supplements providers?

Qualia NAD+ publishes a starting figure of $79/mo. Across the 129 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $170, which puts Qualia NAD+ below the median, toward the cheaper end. The other 39 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Qualia NAD+ review

Runs its own trials

The rare supplement company that tests its own product, publishes the result, and tells you when the result is not peer reviewed yet.

Our verdict

Qualia is doing something almost nobody else in this category does: running randomized, placebo-controlled trials on the finished product rather than borrowing a study about one ingredient, then publishing the write-ups with the dropout numbers and the peer-review status stated plainly. The trials are small, company-funded and unevenly reproduced — the symptom benefit landed in men in the first study and in women in the second. And at $79 for 28 days it sits at the top of the oral range, alongside Wonderfeel Youngr at $88 and well above Tru Niagen at about $39. Worth the premium if you value the fact that someone tested the actual formula. Not worth it if you only want the nicotinamide riboside.

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At a glance

Category: NAD⁺ supplement
Format: Oral precursor
From: $79.00
Dose published: Yes
Prescription: Not required
Compounded: No
Updated: September 2026

What it is

A daily two-capsule formula built around 300 mg of NIAGEN nicotinamide riboside, stacked with two more NAD⁺ precursors — niacinamide and niacin — plus trans-resveratrol, B vitamins, a marine mineral blend and a coffee fruit extract. A 28-day container. Sold by Qualia Life Sciences, the company previously trading as Neurohacker Collective; neurohacker.com now redirects to qualialife.com.

How it works

Retail, not telehealth. There is no intake and no clinician. The company runs a rewards program, a certificate-of-analysis lookup and a money-back guarantee, and sells through retail partners as well as direct.

Pricing transparency

$79.00 for a 56-capsule container, which the page labels a one-time purchase and which lasts 28 days at the stated two-capsule serving. A subscription is $29.00 for the first shipment and $69.00 every four weeks after that; we quote the standing rate rather than the introductory one, because the $29 applies once. The dose is published in full — 300 mg of NIAGEN nicotinamide riboside per serving, alongside 254 mg of niacin equivalents — so the price per milligram is at least calculable. It is still near the top of oral NAD⁺ pricing — Elysium Basis is $65 and Tru Niagen about $39 — and roughly twice what a plain 300 mg nicotinamide riboside capsule sells for.

Branded vs compounded

A dietary supplement, not a drug. It is not FDA-approved, and the FDA does not review supplements for safety or efficacy before sale — the disclaimer appears on Qualia's own pages. Two things on the label are worth knowing before you buy. The formula supplies 254 mg of niacin equivalents, 1,588% of the daily value, and Qualia states on the page that flushing cannot be ruled out. And the coffee fruit extract contributes 28 mg of caffeine a serving, which the product name does not hint at.

Pros and watch-outs

What we like

Has run two randomized, double-blind, placebo-controlled trials on the finished product, not just on one ingredient
Publishes the write-ups with participant dropout stated, and labels them as not yet peer reviewed
Full Supplement Facts panel with every active amount in milligrams
States plainly that the formula can cause niacin flushing
Uses NIAGEN, the nicotinamide riboside ingredient behind most of the published NR research

Watch-outs

$79 for 28 days, against $65 for Elysium Basis and about $39 for Tru Niagen
Both trials are company-run, company-funded and small — 25 and 63 participants analyzed
The symptom benefit appeared in men in the first study and in women in the second, which is what noise looks like
Contains 28 mg of caffeine per serving, easy to miss
254 mg of niacin equivalents is a large dose to take daily without thinking about it

Best for

Someone who wants a finished formula that has actually been tested as a finished formula, and who is willing to pay a premium for that rather than for the milligrams.

Who should look elsewhere

Anyone optimizing cost per milligram, anyone avoiding caffeine, and anyone who reacts badly to niacin. A plain nicotinamide riboside capsule delivers the same 300 mg for roughly half the money.

How Qualia NAD+ compares

A few alternatives worth a look, depending on what you’re optimizing for.

Eden
Knowing the vial size and the real ongoing price
See Eden →
RNK Health
Choosing needle or spray without a price penalty
See RNK Health →
System Labs
Knowing exactly how many milligrams you get
See System Labs →

Compare all providers side by side →

More NAD⁺ precursor supplements reviews: HealthSourceLuvo HealthAVArxRehydra+ WellnessPallas HealthIdgie Health

Laura Bennett

Evidence & trials · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Qualia NAD+’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does Qualia NAD+ cost?: $79.00 for a 56-capsule container, a 28-day supply at two capsules a day, bought outright. On subscription the first shipment is $29.00 and every shipment after that is $69.00, billed every four weeks.
Is the 67% NAD+ increase real?: It comes from Qualia's own second placebo-controlled study, in which 63 participants were analyzed and blood NAD⁺ rose 67% against 4% on placebo. That study is a preprint, not a peer-reviewed paper, and Qualia says so on the page itself. It is also worth seeing the shape of the recruitment: 170 people were enrolled, 102 returned a usable baseline sample, and 63 returned both samples. A company disclosing that attrition in its own marketing write-up is doing something unusual and good, but a 67% figure drawn from 63 self-collected finger-stick samples is a preliminary result, not a settled one.
Will it make me feel better?: The two studies disagree on that, in a revealing way. In the first, men reported improvement on an aging-symptoms scale and women did not. In the second, women improved on the same kind of scale and men showed nothing significant. Qualia's own study page adds that the trial had limited power to detect differences on those secondary measures and that they should be read cautiously. Take that at face value: the NAD⁺ increase is the finding, and the feel-better results are not yet a result.
What is in it besides nicotinamide riboside?: Per two-capsule serving: 300 mg NIAGEN nicotinamide riboside, 254 mg of niacin equivalents from niacinamide and niacin, 50 mg trans-resveratrol, 150 mg of a marine trace mineral blend, 50 mg magnesium, and 40 mg of whole coffee fruit extract supplying 28 mg of caffeine. Then small amounts of thiamine, riboflavin, B6, folate, B12, biotin and pantothenic acid.
Can it cause flushing?: Qualia says it can. The formula contains nicotinic acid, the form of vitamin B3 that causes flushing at doses well above the daily value. The company states on the product page that the amount is below the level at which flushing usually occurs, but that the possibility cannot be ruled out — particularly on an empty stomach. The niacinamide and nicotinamide riboside in the formula do not cause it.
Is Qualia NAD+ expensive compared with other NAD⁺ precursor supplements providers?: Qualia NAD+ publishes a starting figure of $79/mo. Across the 129 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $170, which puts Qualia NAD+ below the median, toward the cheaper end. The other 39 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

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