How much does Direct Meds NAD⁺ cost?

Two plans: $199 a month for a 500 mg vial and $249 a month for 1,000 mg. The “starting at $99” on the landing page is the first month after a $100 discount, not the ongoing rate. Be careful with the “$249/month” on their homepage as well — that sentence is about sublingual semaglutide and only coincidentally matches the 1,000 mg NAD⁺ price.

Which Direct Meds plan is better value?

The larger one, clearly. At $199 for 500 mg you pay about 40 cents a milligram; at $249 for 1,000 mg you pay about 25. The cheaper plan costs roughly 60% more per milligram, so the only reason to take it is if you want to spend less in total rather than less per milligram.

Do they say where the NAD⁺ is made?

Partly, and the two pages do not say quite the same thing. The NAD⁺ product page names ExperienceCare Pharmacy LLC as the pharmacy. The NAD⁺ landing page instead describes a US-based 503B facility, meaning one that compounds in batches and registers with the FDA, but does not name it. Naming a pharmacy at all puts Direct Meds ahead of most of this category, but the two descriptions are worth reconciling before you buy.

No, and Direct Meds' own landing page gets this wrong when it calls NAD⁺ “the fountain of youth peptide”. NAD⁺ is nicotinamide adenine dinucleotide, a coenzyme built from two nucleotides — there is no peptide bond in it. It is a marketing slip rather than a safety problem, but it is the kind of detail worth noticing on a page that is also making bioavailability claims.

Is Direct Meds expensive compared with other NAD⁺ injection providers providers?

Direct Meds publishes a starting figure of $199/mo. Across the 116 NAD⁺ injection providers providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Direct Meds above the median. The other 33 NAD⁺ injection providers providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

PartnerUpdated September 2026

Direct Meds review

Cheaper plan, dearer milligrams

Prints the milligrams next to the price on both its plans. Do the division and the cheaper plan turns out to be the expensive one.

Our verdict

Direct Meds gives you both numbers, which is rarer here than it should be: $199 a month for 500 mg, or $249 for 1,000 mg. Divide, and the entry plan is the bad buy. It works out at 40 cents a milligram against 25 for the larger vial — about 60% more for the privilege of spending less. At 25 cents the bigger plan sits with iThriveMD, above HealthRX at 16 and System Labs at about 15. The pharmacy is named on the product page, which most sellers here will not do. The FDA disclaimer is there too. Then you read the landing page. It calls NAD⁺ a peptide, which it is not. It promises energy and clarity “in days”, and puts the injection at roughly 100% bioavailability — a figure no published study supports.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

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At a glance

Category: NAD⁺ injections
Format: Injection
From: $199/mo
Dose published: Yes
Prescription: Required
Compounded: Yes — not FDA-approved
Pharmacy: Named
Availability: Not published by the provider
LegitScript: Claimed by provider
Updated: September 2026

What it is

A telehealth prescriber whose main business is compounded weight-loss medication — semaglutide and tirzepatide — with an energy-and-wellness line beside it carrying NAD⁺ and sermorelin. NAD⁺ is sold as a subcutaneous injection in two vial strengths, 500 mg and 1,000 mg, with its own landing page separate from the weight-loss funnels.

How it works

An online medical intake reviewed by a licensed provider, with the prescription written only if a provider judges it appropriate. Strength is set by the provider — their FAQ says the practitioner ultimately decides — and the pages describe a standard protocol of a daily injection five days a week rather than a weekly dose. Medications are dispensed by a US compounding pharmacy; there is no insurance billing.

Pricing transparency

Two plans, both stated with their milligram total: $199 a month for 500 mg and $249 a month for 1,000 mg. That is the unusual part — most sellers here give you one number or the other, and Direct Meds gives both, which is what makes the comparison possible at all. The comparison is not flattering to the entry plan: 500 mg at $199 works out to about 40 cents a milligram, while 1,000 mg at $249 is about 25 cents. Two figures on their pages are not the NAD⁺ price. “Starting at $99” is the first month after a $100 discount. And “Plans start at $249/month” on the homepage is a sentence about sublingual semaglutide that happens to land on the same number.

Branded vs compounded

Compounded NAD⁺ for subcutaneous injection at 500 mg or 1,000 mg a vial. The product page names the pharmacy — ExperienceCare Pharmacy LLC, described there as a licensed US compounding pharmacy — while the NAD⁺ lander instead describes the dispenser as a US-based 503B facility — an outsourcing pharmacy that compounds in batches and registers with the FDA — without naming it. The standard FDA disclaimer is present on both: the statements have not been evaluated by the FDA, and the product is not intended to diagnose, treat, cure or prevent any disease.

Pros and watch-outs

What we like

States both the price and the milligrams for each plan, so cost per milligram can be worked out rather than guessed
Names the compounding pharmacy on the product page
Two vial strengths published side by side instead of a single provider-assigned dose
Carries the FDA disclaimer on the product page and the landing page
States LegitScript certification

Watch-outs

The entry plan is the expensive one per milligram — 500 mg at $199 is about 40 cents a milligram against 25 cents for the 1,000 mg plan
Calls NAD⁺ a peptide on its own landing page; NAD⁺ is a dinucleotide coenzyme, not a peptide
Claims roughly 100% bioavailability for the injection, a figure no published human study supports
Promises energy and mental clarity “in days”, which no controlled trial of injected NAD⁺ has ever tested
Disparages oral NAD⁺ precursors as under-dosed, when orals are the only route with randomized human evidence behind them
The headline $99 is a discounted first month, and the homepage's “$249/month” is a semaglutide price
NAD⁺ sits inside a weight-loss business rather than being the main product

Best for

Someone who wants the milligrams printed next to the price and is willing to take the larger vial, where the arithmetic is competitive.

Who should look elsewhere

Anyone shopping on the advertised entry price, which is both a promotional first month and the worse plan per milligram — or anyone who wants marketing claims that match the evidence.

How Direct Meds compares

A few alternatives worth a look, depending on what you’re optimizing for.

Care Bare Rx
Anyone who wants the price up front
See Care Bare Rx →
Breeze Meds
The lowest listed injection price
See Breeze Meds →
CoreAge Rx
The lowest published NAD⁺ price
See CoreAge Rx →

Compare all providers side by side →

More NAD⁺ injection providers reviews: Liquid Mobile IVLIVV NaturalLongevixxLoop HealthLumoraMega Wellness Clinic

Michael Reyes

Cost & access · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Direct Meds’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does Direct Meds NAD⁺ cost?: Two plans: $199 a month for a 500 mg vial and $249 a month for 1,000 mg. The “starting at $99” on the landing page is the first month after a $100 discount, not the ongoing rate. Be careful with the “$249/month” on their homepage as well — that sentence is about sublingual semaglutide and only coincidentally matches the 1,000 mg NAD⁺ price.
Which Direct Meds plan is better value?: The larger one, clearly. At $199 for 500 mg you pay about 40 cents a milligram; at $249 for 1,000 mg you pay about 25. The cheaper plan costs roughly 60% more per milligram, so the only reason to take it is if you want to spend less in total rather than less per milligram.
Do they say where the NAD⁺ is made?: Partly, and the two pages do not say quite the same thing. The NAD⁺ product page names ExperienceCare Pharmacy LLC as the pharmacy. The NAD⁺ landing page instead describes a US-based 503B facility, meaning one that compounds in batches and registers with the FDA, but does not name it. Naming a pharmacy at all puts Direct Meds ahead of most of this category, but the two descriptions are worth reconciling before you buy.
Is NAD⁺ a peptide?: No, and Direct Meds' own landing page gets this wrong when it calls NAD⁺ “the fountain of youth peptide”. NAD⁺ is nicotinamide adenine dinucleotide, a coenzyme built from two nucleotides — there is no peptide bond in it. It is a marketing slip rather than a safety problem, but it is the kind of detail worth noticing on a page that is also making bioavailability claims.
Is Direct Meds expensive compared with other NAD⁺ injection providers providers?: Direct Meds publishes a starting figure of $199/mo. Across the 116 NAD⁺ injection providers providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Direct Meds above the median. The other 33 NAD⁺ injection providers providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every NAD⁺ injection provider.