How much does DoNotAge NMN and NR cost?

Pure NR is $45.00 for 60 capsules at 350 mg each, which at the recommended 700 mg a day is a month. Pure NMN is $80.00 for 60 capsules at 500 mg, a month at the recommended 1,000 mg a day. The powder versions are $87.00 for 100 grams, $150.00 for 183 grams and $699.00 for a kilo; bulk capsule bottles are $240.00 for 366 NR capsules and $440.00 for 366 NMN capsules.

Why is the powder so much cheaper?

Because you are not paying for encapsulation. A hundred grams of NMN powder at $87.00 is 100 days at the recommended gram a day, or roughly $26 a month. The same gram a day in capsules costs $80.00 a month. The molecule, the purity claim and the testing are the same; the difference is a scoop instead of a pill. If cost per milligram is what you are optimizing, that is the single biggest saving available anywhere in this review.

Does NMN reduce neurological decline, as the listing says?

No published human trial shows that it does. We ran three PubMed searches on September 13, 2026 — for NMN and cognitive decline in randomized human trials, for NMN and neurological function in human trials, and for NMN and cognition in older adults against placebo. Nothing came back testing that outcome. What did come back were mechanistic reviews, a protocol for an insomnia trial that had not reported, and a meta-analysis of muscle outcomes. The randomized NMN trials that exist measured blood NAD⁺, walking distance, insulin resistance and questionnaire scores. Neurological decline was not among them.

Is 99.8% purity meaningful?

It is worth having, and it is not the whole story. Purity says what fraction of the powder is the molecule it claims to be — a fair thing to publish, and more than most sellers do. It says nothing about whether the molecule does anything once you swallow it, and a purity figure for a raw material is not the same as an assay of the finished capsule. Renue By Science, elsewhere in this review, publishes the second kind; most of the category publishes neither.

Should I take NMN or NR?

Either. Both are NAD⁺ precursors with randomized, placebo-controlled human trials showing they raise blood NAD⁺, and no head-to-head trial has shown one superior to the other in people. Here, nicotinamide riboside is the cheaper monthly option in capsule form at $45, and NMN is the cheaper option if you are willing to buy powder.

Is DoNotAge expensive compared with other NAD⁺ precursor supplements providers?

DoNotAge publishes a starting figure of $45/mo. Across the 129 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $170, which puts DoNotAge below the median, toward the cheaper end. The other 39 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

DoNotAge review

Clear doses, steep markup

Clean labeling and a fair price on nicotinamide riboside, attached to an NMN capsule that costs three times what the company's own powder does.

Our verdict

DoNotAge gets the basics right where much of this category does not: the milligrams are on the listing, the recommended daily serving is stated, and the same molecules are sold in more than one form so you can see what you are paying for. Two things hold it back. The NMN capsules cost roughly three times what the identical NMN costs as powder on the same website, and the listing carries a claim about reducing neurological decline that no human trial supports. Buy the nicotinamide riboside, or buy the powder.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

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At a glance

Category: NAD⁺ supplement
Format: Oral precursor
From: $45.00
Dose published: Yes
Prescription: Not required
Compounded: No
Updated: September 2026

What it is

A direct-to-consumer longevity supplement brand selling NAD⁺ precursors alongside a broader range — resveratrol, TMG, spermidine, fisetin and others. The two products relevant here are Pure NMN, sold as capsules and as bulk powder, and Pure NR, sold as capsules.

How it works

Retail, not telehealth. No intake, no prescriber, no clinician. Subscriptions are unusual in this category: DoNotAge dispatches them as a single annual shipment sized to a daily dose you choose, rather than a monthly delivery, which is a meaningful commitment to read before you click.

Pricing transparency

Pure NR is the entry point at $45.00 for 60 capsules of 350 mg each — a month at the recommended 700 mg a day. Pure NMN is $80.00 for 60 capsules of 500 mg, which at the recommended 1,000 mg a day is also a month. The same NMN as powder is $87.00 for 100 grams, and at 1 gram a day that is roughly 100 days, or about $26 a month. Identical milligrams, identical company, a third of the price. Larger bottles improve the capsule math — 366 capsules at $440.00 — but never close that gap.

Branded vs compounded

Dietary supplements, not drugs. Neither is FDA-approved and the FDA does not review supplements for safety or efficacy before sale. DoNotAge states 99.8% purity on its NMN and says every batch is third-party tested; the tested purity of a powder is a real quality signal and worth having, though it is a statement about the raw material rather than about what the capsule does in a person.

Pros and watch-outs

What we like

Milligram content and recommended daily serving stated on both NAD⁺ precursor listings
Sells nicotinamide riboside as well as NMN, at a genuinely competitive $45 a month
Offers the same NMN as bulk powder, which is far cheaper per milligram than the capsules
States 99.8% purity and batch third-party testing
Free US shipping over $50

Watch-outs

The NMN capsules cost about three times what the same NMN costs as powder on the same site
The product listing claims NMN "reduces physical and neurological decline," which no human trial shows
Benefit lists run to sleep, immunity, metabolism, liver and cognition — well past what the trials measured
Customer testimonials displayed on the page describe recovery from diagnosed disease
Subscriptions ship as one annual delivery rather than monthly

Best for

Someone buying nicotinamide riboside at a fair monthly price, or someone willing to measure powder and take the large per-milligram saving on NMN.

Who should look elsewhere

Anyone buying NMN in capsules here without checking the powder price first, and anyone who reads the listing's claims about neurological decline as established.

How DoNotAge compares

A few alternatives worth a look, depending on what you’re optimizing for.

Eden
Knowing the vial size and the real ongoing price
See Eden →
RNK Health
Choosing needle or spray without a price penalty
See RNK Health →
System Labs
Knowing exactly how many milligrams you get
See System Labs →

Compare all providers side by side →

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Michael Reyes

Cost & access · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of DoNotAge’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does DoNotAge NMN and NR cost?: Pure NR is $45.00 for 60 capsules at 350 mg each, which at the recommended 700 mg a day is a month. Pure NMN is $80.00 for 60 capsules at 500 mg, a month at the recommended 1,000 mg a day. The powder versions are $87.00 for 100 grams, $150.00 for 183 grams and $699.00 for a kilo; bulk capsule bottles are $240.00 for 366 NR capsules and $440.00 for 366 NMN capsules.
Why is the powder so much cheaper?: Because you are not paying for encapsulation. A hundred grams of NMN powder at $87.00 is 100 days at the recommended gram a day, or roughly $26 a month. The same gram a day in capsules costs $80.00 a month. The molecule, the purity claim and the testing are the same; the difference is a scoop instead of a pill. If cost per milligram is what you are optimizing, that is the single biggest saving available anywhere in this review.
Does NMN reduce neurological decline, as the listing says?: No published human trial shows that it does. We ran three PubMed searches on September 13, 2026 — for NMN and cognitive decline in randomized human trials, for NMN and neurological function in human trials, and for NMN and cognition in older adults against placebo. Nothing came back testing that outcome. What did come back were mechanistic reviews, a protocol for an insomnia trial that had not reported, and a meta-analysis of muscle outcomes. The randomized NMN trials that exist measured blood NAD⁺, walking distance, insulin resistance and questionnaire scores. Neurological decline was not among them.
Is 99.8% purity meaningful?: It is worth having, and it is not the whole story. Purity says what fraction of the powder is the molecule it claims to be — a fair thing to publish, and more than most sellers do. It says nothing about whether the molecule does anything once you swallow it, and a purity figure for a raw material is not the same as an assay of the finished capsule. Renue By Science, elsewhere in this review, publishes the second kind; most of the category publishes neither.
Should I take NMN or NR?: Either. Both are NAD⁺ precursors with randomized, placebo-controlled human trials showing they raise blood NAD⁺, and no head-to-head trial has shown one superior to the other in people. Here, nicotinamide riboside is the cheaper monthly option in capsule form at $45, and NMN is the cheaper option if you are willing to buy powder.
Is DoNotAge expensive compared with other NAD⁺ precursor supplements providers?: DoNotAge publishes a starting figure of $45/mo. Across the 129 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $170, which puts DoNotAge below the median, toward the cheaper end. The other 39 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every NAD⁺ supplement.