Is Effepharm really running the world's only human NMN trial?

No. We checked on September 13, 2026. A PubMed search for nicotinamide mononucleotide in the title or abstract, limited to randomized controlled trials, returns seventeen records. They include a 2021 trial in Science by Yoshino and colleagues at Washington University School of Medicine, a 2023 multicenter dose-ranging trial in GeroScience run by Yi and colleagues for Abinopharm, and a 2023 twelve-week trial in Scientific Reports from DHC Corporation Laboratories in Japan. Effepharm's own Uthever trial, published in Frontiers in Aging in 2022, is one of the seventeen — a real study, but plainly not the only one.

How much does Partiqlar Pure NMN cost?

$64.99 for one bottle of 60 capsules, shown against a $79.99 regular price. Three bottles are $149.97 and six are $259.99. At the recommended starting dose of one capsule a day the bottle is two months; at two capsules a day it is one. The bottle holds 30 grams of NMN, about $2.17 a gram.

What about the 97% and 94% figures?

They come from what the page calls a mass survey of 12,198 customers — and the sentence introducing them says those customers "rated their NR experience." NR is nicotinamide riboside, a different NAD⁺ precursor, and it is not what this bottle contains. Either the copy was written for another product and never changed, or the survey really is about a different supplement. Either way, a self-reported customer survey with no methodology attached is not evidence of an effect, and these particular numbers are not evidence about this particular product.

Is 500 mg a day the right dose?

It is within the range that has been tested, and close to where the strongest signal has been found. In the 2023 GeroScience trial, 80 healthy middle-aged adults took placebo, 300, 600 or 900 mg daily for 60 days; blood NAD rose significantly on all three doses, six-minute walking distance improved against placebo, and the authors concluded efficacy was highest at 600 mg. Doses up to 900 mg were well tolerated. Partiqlar's advice to start at one capsule and consider two later is sensible on those numbers.

Why do I see a different price if I arrive from an advertisement?

Because there are several near-identical listings for the same product. Alongside the main page, the catalog carries variants with handles naming press mentions, priced at $63.46 against the same $79.99 comparison figure, and each one is tagged noindex so it stays out of search results. They are advertising landing pages. The practical effect is that the price you see depends on which door you came in through, which is worth knowing before you decide $64.99 is the rate.

Is Partiqlar expensive compared with other NAD⁺ precursor supplements providers?

Partiqlar publishes a starting figure of $64.99/mo. Across the 116 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Partiqlar below the median, toward the cheaper end. The other 33 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Partiqlar review

Fair dose, false exclusivity

Five hundred milligrams a capsule at a defensible price, wrapped in a claim about clinical research that is simply not true.

Our verdict

The product underneath the marketing is sound: 500 mg of NMN per capsule, 60 capsules, $64.99, a little over two dollars a gram. Then the page tells you that its ingredient supplier is "conducting the world's only human clinical trial on Nicotinamide Mononucleotide." That is checkable, and it is false — PubMed indexes seventeen randomized controlled trials of NMN, run by university and company groups across three continents. The page also reports a customer survey about "their NR experience" on a product that is not NR, counts down a stock number, and offers three different discounts at once. Good dose, bad page.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

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At a glance

Category: NMN supplement
Format: Oral precursor
From: $64.99
Dose published: Yes
Prescription: Not required
Compounded: No
Updated: September 2026

What it is

A single-ingredient NMN capsule: 500 mg of β-nicotinamide mononucleotide, 60 capsules, in a vegetable cellulose shell that Partiqlar says is enteric coated. The recommended start is one capsule a day, moving to two after several weeks. The NMN itself is sourced from Effepharm, the Shanghai manufacturer behind the Uthever ingredient.

How it works

Retail, direct to consumer, with a subscription upsell attached to almost every surface of the page. Partiqlar states that its US manufacturing facilities are certified by NSF and UL for GMP compliance and that every batch is third-party tested for potency, with purity above 99% verified by chromatographic and NMR methods. No certificate is published to read.

Pricing transparency

$64.99 for one bottle, marked against a $79.99 compare-at price, with three bottles at $149.97 and six at $259.99. We record $64.99: it is the standing one-time rate and the figure in the page's own structured data. Everything else on the page pushes below it — a 10% checkout code, a subscription pitch advertised as up to 57% off in one banner and up to 69% off in another, and a stock warning saying only 33 bottles remain at this price. At 500 mg a capsule the bottle holds 30 grams of NMN, which is about $2.17 per gram, or roughly $65 a month at one capsule a day and $130 at two.

Branded vs compounded

A dietary supplement, not FDA-approved and not reviewed by the FDA for safety or efficacy before sale. The claims are where this page goes wrong, and they go wrong in three distinguishable ways. There is the exclusivity claim about the world's only NMN trial, which is false. There are flat efficacy statements printed on the product imagery — that NMN improves glucose metabolism and insulin sensitivity, improves muscle strength and aerobic capacity, helps in DNA repair — presented as properties of the molecule rather than findings from particular trials in particular populations. And there is a customer survey reporting that 97% felt more energy in week one and 94% noticed fewer wrinkles by week three, which describes, in the page's own words, how 12,198 customers "rated their NR experience" — nicotinamide riboside, a different molecule from the one in the bottle.

Pros and watch-outs

What we like

500 mg of NMN in a single capsule, so one pill a day reaches a trial-scale dose
About $2.17 per gram of NMN, which is mid-range rather than premium
Single ingredient with no proprietary blend and no second active sharing the label
Names its ingredient supplier rather than leaving the source unstated
States NSF and UL GMP certification for its US manufacturing

Watch-outs

Claims its supplier is running the world's only human NMN trial; PubMed indexes seventeen randomized ones
Reports a survey of customers' nicotinamide riboside experience on a nicotinamide mononucleotide page
Prints outcome claims — DNA repair, insulin sensitivity, aerobic capacity — as settled properties of NMN
A scarcity counter, a coupon code and two different subscription discount figures on one page
Publishes no certificate of analysis despite describing its testing methods in detail
The enteric coating claim is asserted with nothing behind it

Best for

A buyer who wants 500 mg in one capsule from a named ingredient source and is able to ignore everything written around the product.

Who should look elsewhere

Anyone who takes a seller's research claims as a reason to buy. On this page they are the least reliable thing on it.

How Partiqlar compares

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Laura Bennett

Evidence & trials · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Partiqlar’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

Is Effepharm really running the world's only human NMN trial?: No. We checked on September 13, 2026. A PubMed search for nicotinamide mononucleotide in the title or abstract, limited to randomized controlled trials, returns seventeen records. They include a 2021 trial in Science by Yoshino and colleagues at Washington University School of Medicine, a 2023 multicenter dose-ranging trial in GeroScience run by Yi and colleagues for Abinopharm, and a 2023 twelve-week trial in Scientific Reports from DHC Corporation Laboratories in Japan. Effepharm's own Uthever trial, published in Frontiers in Aging in 2022, is one of the seventeen — a real study, but plainly not the only one.
How much does Partiqlar Pure NMN cost?: $64.99 for one bottle of 60 capsules, shown against a $79.99 regular price. Three bottles are $149.97 and six are $259.99. At the recommended starting dose of one capsule a day the bottle is two months; at two capsules a day it is one. The bottle holds 30 grams of NMN, about $2.17 a gram.
What about the 97% and 94% figures?: They come from what the page calls a mass survey of 12,198 customers — and the sentence introducing them says those customers "rated their NR experience." NR is nicotinamide riboside, a different NAD⁺ precursor, and it is not what this bottle contains. Either the copy was written for another product and never changed, or the survey really is about a different supplement. Either way, a self-reported customer survey with no methodology attached is not evidence of an effect, and these particular numbers are not evidence about this particular product.
Is 500 mg a day the right dose?: It is within the range that has been tested, and close to where the strongest signal has been found. In the 2023 GeroScience trial, 80 healthy middle-aged adults took placebo, 300, 600 or 900 mg daily for 60 days; blood NAD rose significantly on all three doses, six-minute walking distance improved against placebo, and the authors concluded efficacy was highest at 600 mg. Doses up to 900 mg were well tolerated. Partiqlar's advice to start at one capsule and consider two later is sensible on those numbers.
Why do I see a different price if I arrive from an advertisement?: Because there are several near-identical listings for the same product. Alongside the main page, the catalog carries variants with handles naming press mentions, priced at $63.46 against the same $79.99 comparison figure, and each one is tagged noindex so it stays out of search results. They are advertising landing pages. The practical effect is that the price you see depends on which door you came in through, which is worth knowing before you decide $64.99 is the rate.
Is Partiqlar expensive compared with other NAD⁺ precursor supplements providers?: Partiqlar publishes a starting figure of $64.99/mo. Across the 116 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Partiqlar below the median, toward the cheaper end. The other 33 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every NAD⁺ supplement.