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James Harper
Five ways to buy NAD⁺, and the very different amounts of evidence behind each one.
James compares delivery routes — subcutaneous injection, IV infusion, nasal spray, transdermal patch and oral precursor — on the only question that matters: whether there is published human evidence that the format delivers anything at all.
What they cover
- Routes of administration and bioavailability
- Subcutaneous and intravenous NAD⁺ protocols
- Intranasal and transdermal delivery
- Oral precursor absorption
- Compounded versus FDA-approved products
- Pharmacokinetics of coenzyme precursors
Articles by James Harper
14 pieces- Does NAD⁺ actually decline with age?Evidence
- What are NAD⁺ injections? How the shot works, what it costs, and what it is legallyFormats
- NAD⁺ dosage: the doses used in trials, and why no honest chart existsFormats
- NAD⁺ IV therapy: what a drip actually does, and what it costs youFormats
- NAD⁺ therapy: the five things sold under that name, and what each is worthFormats
- Why people stop taking NMN — and what the evidence says about each reasonEvidence
- NMN dosage: every dose used in a published human trial, and no chartFormats
- NAD⁺ IV therapy benefits: what was in the bag, and what was measuredEvidence
- NAD⁺ injection dosage: what sellers publish vs what trials usedFormats
- Where to inject NAD⁺: subcutaneous, intramuscular, and what no trial has testedFormats
- NAD⁺ 500 mg vs 1000 mg: is the higher tier supported by anything?Formats
- NAD⁺ skincare: niacinamide has the data, NAD⁺ itself does notFormats
- NAD⁺ nasal spray vs injection: cheaper at the same seller, and unmeasured in peopleFormats
- NAD⁺ nasal spray: what it is, how it is dosed, and what nobody has measuredFormats