People searching for a NAD⁺ dosage chart are looking for something that does not exist, and the reason it does not exist is worth understanding before you go looking somewhere less careful.
A dosing chart for an approved drug comes from trials that established what dose produces what effect at what risk. Commercial NAD⁺ wellness injections have no established dosing regimen from such trials. These are compounded preparations, not FDA-approved, with no controlled outcome studies behind the benefits it is sold for — so there is nothing for a chart to be built from. Any site publishing one is inventing it.
What we can give you is the real thing underneath: the doses actual researchers administered, and the doses actual products state. Both are attributed. Neither is a recommendation, and the decision belongs to a clinician who knows your history.
Does the “peptide” label change the dose question?
No. NAD⁺ is a dinucleotide coenzyme, not a peptide. Calling it “peptide therapy” does not make a peptide dose, body-weight formula or cycling schedule applicable. The molecular classification explainer covers why the label is misleading.
This page compares published study exposures across compounds and populations. For the quantities sellers actually advertise, use the injection dose-disclosure comparison. For the different arithmetic of a milligram of NR, NMN or NAD⁺, use the molecular-equivalent explanation. None of these comparisons supplies a personal treatment schedule.
Doses used in published human trials
These are examples of doses given in published human studies, each attributed. None is a recommendation, and the decision belongs to a clinician who knows your history.
NMN, 250 mg daily. The two trials that measured sleep and walking both used this. One randomized 108 older Japanese adults to NMN or placebo, taken either in the morning or the afternoon, for 12 weeks (n = 108) [4]. The other gave 250 mg a day to 60 older adults for 12 weeks [5].
NMN, 300 to 900 mg daily. A randomized, multicenter, double-blind, placebo-controlled trial randomized 80 healthy middle-aged adults to placebo or 300, 600 or 900 mg once daily for 60 days. Blood NAD⁺ rose significantly in every NMN arm at day 30 and day 60, against placebo and baseline (all p ≤ 0.001)[1].
NMN, 300 to 1,200 mg daily. A six-week trial in 48 amateur runners used 300, 600 and 1,200 mg against placebo alongside training[6].
NMN, 1,250 mg daily. A safety study gave 1,250 mg of β-NMN orally once daily for up to four weeks to 31 healthy adults aged 20 to 65, and reported no severe adverse events over the study period [2].
NR, 2,000 mg daily. A 12-week randomized, placebo-controlled trial gave 40 obese, insulin-resistant men nicotinamide riboside at 1,000 mg twice daily. The paper concluded that dose “appears safe” while finding no improvement in insulin sensitivity or whole-body glucose metabolism [7].
NR, 3,000 mg daily. The NR-SAFE trial randomized 20 people with Parkinson’s disease to NR 1,500 mg twice daily or placebo for four weeks. Its own background notes that doses above 2,000 mg daily had not previously been tested in humans. NR was well tolerated with no moderate or severe adverse events, and blood NAD⁺ rose up to fivefold; the authors support extending the range to 3,000 mg a day in phase II trials [3].
Intravenous NAD⁺, a pharmacokinetic example. A human pharmacokinetic pilot ran NAD⁺ at 3 µmol per minute for six hours. Notably, plasma NAD⁺ did not change until after two hours[8].
NR, retail serving. Tru Niagen sells a 300 mg capsule it describes as its minimum daily recommended serving. That is a manufacturer’s serving size, not a trial dose.
What injectable providers state
Use the questions-to-ask checklist to record the quantity, concentration, dispensing pharmacy and follow-up arrangements before comparing offers.
Here is the finding that should shape how you shop: among the NAD⁺ injection providers we can verify, almost none publish the dose their monthly price buys. They publish $169 or $199 a month and leave the milligrams unstated.
That makes their prices genuinely incomparable, and it is the single most useful question to put to any of them before paying. If you get a number, our cost-per-milligram calculator turns competing offers into a figure you can line up. If you do not get a number, you have learned something about how they sell.
Why we will not publish a chart
A milligram-per-kilogram table would imply a validated relationship between dose, benefit and risk. The studies above do not establish that relationship for commercial wellness injections. A published research exposure is not a recommendation for a different patient, formulation or purpose.
Take the trial doses above to a clinician and ask what is appropriate for you. If you want the cheaper, better-evidenced route first, that is an oral precursor — and see what is known about safety before starting anything. If your question is the blunter one, how much should I take answers it without the trial tables.