How much does Quicksilver NAD+ Gold cost?

$45.00 for the 30 mL bottle and $68.50 for the 50 mL, both shown as regular prices with no discount applied. The 30 mL bottle holds 30 one-milliliter servings, so at one serving a day it is a month for $45.

How much NMN is in a serving?

50 mg, alongside 50 mg of trimethylglycine, in a 1 mL serving taken as two pumps. The bottle holds 1.5 grams of NMN in total, which is about $30 per gram. For comparison, plain NMN capsules in this category run from well under a dollar to a few dollars per gram.

Is 50 mg enough to do anything?

Every randomized NMN trial we read used a considerably larger amount. Katayoshi and colleagues, in Scientific Reports in 2023: 125 mg twice daily over 12 weeks. The 2022 Uthever study in Frontiers in Aging: 300 mg a day for 60 days. And Yi and colleagues in GeroScience in 2023, testing placebo against 300, 600 and 900 mg a day, found the effect strongest at 600. Quicksilver's case is that liposomal sublingual delivery means you need less, and that is a coherent argument — it is simply not one that has been run against a swallowed capsule in people.

What is the "recent scientific breakthrough" the page refers to?

Almost certainly the 2019 Nature Metabolism paper by Grozio and colleagues identifying Slc12a8 as a nicotinamide mononucleotide transporter. We read the abstract in September 2026: the gene is shown to be highly expressed in the mouse small intestine, knocking it down abolishes NMN uptake in vitro and in vivo, and its loss reduces NAD⁺ in the mouse jejunum and ileum. It is careful mouse work. The page's phrasing — that NMN "can be transported directly into cells to rapidly produce NAD+" — reads as an established fact about the person buying the bottle, which is not what the paper shows.

Does it need to be refrigerated?

Yes. The product ships with ice packs and the page says to refrigerate on receipt. That is consistent with a liposomal preparation, which is a physical structure that can break down, rather than a dry powder in a capsule. It also means the bottle is less forgiving of a warm porch, a holiday or a travel bag than any of the capsule products in this category.

Is Quicksilver NAD Gold legit?

FDA has a warning letter on record against Quicksilver Scientific, the company behind quicksilverscientific.com, issued October 13, 2021 as letter 612476; it is linked further down this page. On this desk a warning letter discloses, it does not disqualify — it is a public record to read before you decide. Quicksilver NAD Gold is a NMN supplement service. What our record does not establish: which states it serves, which medications it dispenses, whether it bills insurance and how its intake works. Ask for those in writing before you pay.

Is Quicksilver NAD Gold expensive compared with other NAD⁺ precursor supplements?

Quicksilver NAD Gold publishes a starting figure of $45/mo. Across the 109 NAD⁺ precursor supplements we review that publish a starting price on the same billing basis, those run $17.97/mo to $649/mo with a median of $158.93/mo, which puts Quicksilver NAD Gold below the median, toward the cheaper end. The other 41 NAD⁺ precursor supplements we review do not have a comparable published starting price in our records, so they are excluded. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Quicksilver NAD Gold review

Small dose, big premium

A sublingual liposomal NMN that publishes its whole label — and the label says fifty milligrams.

Our verdict

Quicksilver publishes the panel, so you can see exactly what $45 buys. One milliliter, twice-pumped under the tongue. Fifty milligrams of NMN and fifty of TMG, thirty times over. That is a gram and a half in the bottle — near thirty dollars a gram, roughly twenty times what a plain capsule costs, and a fraction of the dose used in the published NMN trials. The liposomal-and-sublingual argument is that you need far less. It is a real argument. It has also never been tested in humans against a swallowed capsule. And the page's own instruction is to "repeat to desired dosage", which leaves you guessing at the one number the format is supposed to settle.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; commissions do not change evidence scores or editorial verdicts. How we make money.

Check availability →

FDA warning letter on record — public record, does not change our verdict.

At a glance

Category: NMN supplement
Format: Oral precursor
From: $45.00
Dose published: Yes
Prescription: Not required
Compounded: No
FDA: Warning letter on record
Updated: September 2026

What it is

A sublingual liquid rather than a capsule: a liposomal preparation held under the tongue for thirty to ninety seconds before swallowing, dosed by pump. Two pumps make a 1 mL serving carrying 50 mg of NMN and 50 mg of trimethylglycine in water, glycerin, ethanol, purified phospholipids and vitamin E. Thirty servings in the 30 mL bottle, fifty in the 50 mL. It ships with ice packs and needs refrigerating on arrival.

How it works

Retail, sold direct and also through practitioners. No intake or prescriber. Quicksilver states an NSF GMP-certified facility and carries tested-free-of badges for gluten, allergens, GMOs and soy protein, but publishes no certificate of analysis or batch report on the product page.

Pricing transparency

$45.00 for 30 mL, listed as both regular and sale price, with the 50 mL bottle at $68.50, which is a modestly better rate — $1.37 a milliliter against $1.50. Thirty servings at 50 mg is 1.5 grams of NMN, so the bottle is about $30 per gram of the active. That is the figure to hold in mind, because the suggested use does not stop at one serving: it says to repeat to your desired dosage. Anyone chasing the 250 mg to 600 mg daily doses used in published trials would empty a $45 bottle in under a week.

Branded vs compounded

A dietary supplement, not FDA-approved and not reviewed by the FDA for safety or efficacy before sale. Two claims on the page are worth separating. The first is hedged and mostly fine — "the only liposomal NMN that we know of" is a statement about the company's knowledge, though other liposomal NMN capsules are on sale. The second is not hedged: "According to a recent scientific breakthrough, NMN can be transported directly into cells to rapidly produce NAD+." That refers to the identification of Slc12a8 as an NMN transporter, published by Grozio and colleagues in Nature Metabolism in 2019. The gene was characterized in the mouse small intestine. Presenting it as settled human physiology, on a page selling a human a 50 mg dose, is a reach.

FDA warning letter on record

The FDA issued a warning letter naming Quicksilver Scientific, the company behind quicksilverscientific.com — the site this review covers.

Letter 612476, issued October 13, 2021 — read it on fda.gov

We publish this because it is a matter of public record and a reader weighing this provider should have it. A warning letter is the FDA setting out alleged violations; it is not a court finding, and a company may have responded or corrected since. It does not remove Quicksilver NAD Gold from our rankings, and it does not change our verdict — read the letter and decide for yourself.

Pros and watch-outs

What we like

Publishes the complete panel: serving size, servings per container and both actives in milligrams
Sublingual delivery, which at least gives the low dose a mechanism to argue from
Pairs the NMN with an equal weight of TMG, the methyl donor usually taken alongside it
Short, fully named ingredient list with no proprietary blend
Pump dosing lets you take a fraction of a serving, which capsules do not

Watch-outs

50 mg per serving, well below the doses used in the published human NMN trials we read
About $30 per gram of NMN, an order of magnitude above capsule pricing
"Repeat to desired dosage" gives no guidance on what the desired dosage is
States a mouse transporter finding as though it described human absorption
Needs refrigeration and ships with ice packs, which constrains how you buy and store it
No certificate of analysis or batch report published

Best for

Someone who cannot or will not swallow capsules, wants a liposomal sublingual format from a brand that specializes in them, and is treating NMN as one small part of a stack rather than a dose to be matched to a trial.

Who should look elsewhere

Anyone aiming at a trial-sized daily dose, and anyone buying on cost per milligram. At this concentration the arithmetic does not work.

How Quicksilver NAD Gold compares

A few alternatives worth a look, depending on what you’re optimizing for.

Eden
Knowing the vial size and the real ongoing price
See Eden →
RNK Health
Choosing needle or spray without a price penalty
See RNK Health →
ShedRx
A mid-range price you can find without an intake
See ShedRx →

Compare all providers side by side →

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James Harper

Formats & delivery · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Quicksilver NAD Gold’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does Quicksilver NAD+ Gold cost?: $45.00 for the 30 mL bottle and $68.50 for the 50 mL, both shown as regular prices with no discount applied. The 30 mL bottle holds 30 one-milliliter servings, so at one serving a day it is a month for $45.
How much NMN is in a serving?: 50 mg, alongside 50 mg of trimethylglycine, in a 1 mL serving taken as two pumps. The bottle holds 1.5 grams of NMN in total, which is about $30 per gram. For comparison, plain NMN capsules in this category run from well under a dollar to a few dollars per gram.
Is 50 mg enough to do anything?: Every randomized NMN trial we read used a considerably larger amount. Katayoshi and colleagues, in Scientific Reports in 2023: 125 mg twice daily over 12 weeks. The 2022 Uthever study in Frontiers in Aging: 300 mg a day for 60 days. And Yi and colleagues in GeroScience in 2023, testing placebo against 300, 600 and 900 mg a day, found the effect strongest at 600. Quicksilver's case is that liposomal sublingual delivery means you need less, and that is a coherent argument — it is simply not one that has been run against a swallowed capsule in people.
What is the "recent scientific breakthrough" the page refers to?: Almost certainly the 2019 Nature Metabolism paper by Grozio and colleagues identifying Slc12a8 as a nicotinamide mononucleotide transporter. We read the abstract in September 2026: the gene is shown to be highly expressed in the mouse small intestine, knocking it down abolishes NMN uptake in vitro and in vivo, and its loss reduces NAD⁺ in the mouse jejunum and ileum. It is careful mouse work. The page's phrasing — that NMN "can be transported directly into cells to rapidly produce NAD+" — reads as an established fact about the person buying the bottle, which is not what the paper shows.
Does it need to be refrigerated?: Yes. The product ships with ice packs and the page says to refrigerate on receipt. That is consistent with a liposomal preparation, which is a physical structure that can break down, rather than a dry powder in a capsule. It also means the bottle is less forgiving of a warm porch, a holiday or a travel bag than any of the capsule products in this category.
Is Quicksilver NAD Gold legit?: FDA has a warning letter on record against Quicksilver Scientific, the company behind quicksilverscientific.com, issued October 13, 2021 as letter 612476; it is linked further down this page. On this desk a warning letter discloses, it does not disqualify — it is a public record to read before you decide. Quicksilver NAD Gold is a NMN supplement service. What our record does not establish: which states it serves, which medications it dispenses, whether it bills insurance and how its intake works. Ask for those in writing before you pay.
Is Quicksilver NAD Gold expensive compared with other NAD⁺ precursor supplements?: Quicksilver NAD Gold publishes a starting figure of $45/mo. Across the 109 NAD⁺ precursor supplements we review that publish a starting price on the same billing basis, those run $17.97/mo to $649/mo with a median of $158.93/mo, which puts Quicksilver NAD Gold below the median, toward the cheaper end. The other 41 NAD⁺ precursor supplements we review do not have a comparable published starting price in our records, so they are excluded. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every NAD⁺ supplement.