How much does Renue By Science cost?

The NMN products start at $54.95 — for 100 grams of powder at 500 mg per scoop, or for 240 fast-dissolve tablets. Liposomal NMN capsules are $64.95, the nicotinamide riboside powder is $79.00 at 1,000 mg a serving, and NAD+ Complete, which combines NMN, NAD⁺, NR and trigonelline, is $84.95. Shipping is free on US orders over $50.

Is sublingual or liposomal NMN really better absorbed?

Not on the evidence available. We ran three PubMed searches on September 13, 2026 — for randomized human trials of liposomal NMN bioavailability, for sublingual versus oral NMN in humans, and for measured oral NMN bioavailability in humans. The first two returned nothing at all. The one direct human comparison that does exist, a randomized crossover in 14 healthy men published in Scientific Reports in 2026, found no significant difference in blood NMN, nicotinamide or NAD⁺ between the sublingual and oral routes; only two downstream breakdown products rose faster sublingually. That is a long way from the absorption advantage the format is sold on.

What is the best value in their range?

The plain NMN powder. At $54.95 for 100 grams and a 500 mg scoop, that is 200 servings, which works out cheaper per milligram than anything else in this review — including their own capsules and tablets. If you are buying NMN for the NMN rather than for the delivery system, this is where the money goes furthest.

How good is their third-party testing?

Thorough, and unusually so. Product pages list the batch number currently shipping alongside dated certificates covering potency, heavy metals and microbiology, plus an archive of previous batches. The company's own argument for why that matters is correct: a certificate for a raw ingredient sample tells you nothing about the finished capsule, and most sellers publish only the former, if anything.

Should I buy their NAD+ Complete or nasal spray instead of plain NMN?

Not on current evidence. NAD+ Complete stacks NMN, NAD⁺, nicotinamide riboside and trigonelline for $84.95, and the nasal spray delivers NAD⁺ itself for $59.95. Neither NAD⁺ taken by mouth nor NAD⁺ taken intranasally has a published human trial showing it raises blood NAD⁺. The NMN and nicotinamide riboside in the range do have that evidence, and they cost less.

Updated September 2026

Renue By Science review

Documented, premise unproven

Publishes a dated lab report for the specific batch in your bottle, which is rare anywhere in supplements — built on a delivery claim the one human head-to-head does not support.

Our verdict

On quality documentation, Renue By Science is the best in this category and it is not close: every product page lists batch numbers tied to dated certificates of analysis for potency, heavy metals and microbiology, and the company says outright that testing a raw ingredient and calling it proof is not the same as testing what went in the bottle. It is right about that. Where it overreaches is the reason the whole catalog exists — sublingual, liposomal and intranasal delivery. The only randomized human comparison of sublingual against ordinary oral NMN found no difference in blood NMN, nicotinamide or NAD⁺. Buy here for the transparency, not for the route.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

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At a glance

Category: NAD⁺ supplement
Format: Oral precursor
From: $54.95
Dose published: Yes
Prescription: Not required
Compounded: No
Updated: September 2026

What it is

A specialist NAD⁺ manufacturer selling precursors in formats other companies do not offer: sublingual fast-dissolve tablets, powder-based liposomal capsules, a nasal spray, a transdermal gel, enteric-coated capsules and plain powders. The line covers NMN, nicotinamide riboside, trigonelline and NAD⁺ itself, alone and in combination.

How it works

Retail, not telehealth. No intake, no prescriber, no clinician. Free shipping on US orders over $50. The company states its products are tested in ISO-certified and cGMP-certified laboratories, and publishes the batch-level reports rather than describing them.

Pricing transparency

The NMN line opens at $54.95 — either 100 grams of pure powder at 500 mg a scoop, or 240 fast-dissolve tablets — and runs up through liposomal capsules at $64.95, a nicotinamide riboside powder at 1,000 mg a serving for $79.00, and the four-in-one NAD+ Complete at $84.95. A trigonelline bottle sits just below the range at $51.95, and a combined protocol bundle at $207.00. Doses are published on every page in milligrams, so per-milligram math is possible throughout: the $54.95 powder works out to 200 servings of 500 mg, a shade over 27 cents a serving and the lowest verified cost per milligram of NMN in this review.

Branded vs compounded

Dietary supplements, not drugs. None of them is FDA-approved and the FDA does not review supplements for safety or efficacy before sale. What Renue offers instead is unusually specific: a batch number on the bottle that matches a published certificate of analysis, with the test date and the assay named. Several products list six or more historical batch reports. That answers the question of what is in the capsule better than anyone else here — it does not answer whether the delivery format does what the marketing says.

Pros and watch-outs

What we like

Publishes dated certificates of analysis tied to the batch number on your bottle
Tests the finished product, not just the raw ingredient, and says why that distinction matters
Milligram doses published on every product page
The lowest verified cost per milligram of NMN in this review — $54.95 for 200 servings of 500 mg
The widest format range in the category: sublingual, liposomal, enteric, nasal, transdermal

Watch-outs

The bioavailability advantage the whole catalog is built on has not been demonstrated in humans
The one randomized human comparison of sublingual against oral NMN found no difference in blood NAD⁺
Sells NAD⁺ itself orally and intranasally, formats with no controlled human outcome data
A large catalog makes it easy to buy an expensive format instead of an effective dose
Supplements, so no FDA review of safety or efficacy before sale

Best for

Someone who cares most about knowing exactly what is in the bottle, and who wants NMN at the lowest verified cost per milligram. The plain powder is the best value in this category.

Who should look elsewhere

Anyone paying a premium specifically for sublingual or liposomal absorption. That premium currently buys a mechanism, not a measured result.

How Renue By Science compares

A few alternatives worth a look, depending on what you’re optimizing for.

Care Bare Rx
Anyone who wants the price up front
See Care Bare Rx →
Breeze Meds
The lowest listed injection price
See Breeze Meds →
CoreAge Rx
The lowest published NAD⁺ price
See CoreAge Rx →

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James Harper

Formats & delivery · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Renue By Science’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

How much does Renue By Science cost?: The NMN products start at $54.95 — for 100 grams of powder at 500 mg per scoop, or for 240 fast-dissolve tablets. Liposomal NMN capsules are $64.95, the nicotinamide riboside powder is $79.00 at 1,000 mg a serving, and NAD+ Complete, which combines NMN, NAD⁺, NR and trigonelline, is $84.95. Shipping is free on US orders over $50.
Is sublingual or liposomal NMN really better absorbed?: Not on the evidence available. We ran three PubMed searches on September 13, 2026 — for randomized human trials of liposomal NMN bioavailability, for sublingual versus oral NMN in humans, and for measured oral NMN bioavailability in humans. The first two returned nothing at all. The one direct human comparison that does exist, a randomized crossover in 14 healthy men published in Scientific Reports in 2026, found no significant difference in blood NMN, nicotinamide or NAD⁺ between the sublingual and oral routes; only two downstream breakdown products rose faster sublingually. That is a long way from the absorption advantage the format is sold on.
What is the best value in their range?: The plain NMN powder. At $54.95 for 100 grams and a 500 mg scoop, that is 200 servings, which works out cheaper per milligram than anything else in this review — including their own capsules and tablets. If you are buying NMN for the NMN rather than for the delivery system, this is where the money goes furthest.
How good is their third-party testing?: Thorough, and unusually so. Product pages list the batch number currently shipping alongside dated certificates covering potency, heavy metals and microbiology, plus an archive of previous batches. The company's own argument for why that matters is correct: a certificate for a raw ingredient sample tells you nothing about the finished capsule, and most sellers publish only the former, if anything.
Should I buy their NAD+ Complete or nasal spray instead of plain NMN?: Not on current evidence. NAD+ Complete stacks NMN, NAD⁺, nicotinamide riboside and trigonelline for $84.95, and the nasal spray delivers NAD⁺ itself for $59.95. Neither NAD⁺ taken by mouth nor NAD⁺ taken intranasally has a published human trial showing it raises blood NAD⁺. The NMN and nicotinamide riboside in the range do have that evidence, and they cost less.

Check availability →

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