What is on the certificate of analysis?

Numbers. We opened the batch NMNC2CS1042425 certificate in September 2026. It names the lot, the raw material batch, the production and report dates and a best-by date of April 2028. Identity was confirmed by infrared spectroscopy at a 99% match to the library standard against a 95% specification. The assay, by ultraviolet-visible spectroscopy, reports 283 mg of nicotinamide mononucleotide per capsule against a specification of at least 250 mg. Loss on drying was 1%, water activity 0.37, and arsenic, cadmium, mercury and lead were each measured by ICP-MS well under the 0.5 ppm limit. It is signed by a named quality liaison and carries an ILAC-MRA mark and a PJLA accreditation number.

Is Omnient Labs independent?

Not in the sense most people mean, and Nootropics Depot says so itself. Its own page about its testing partners states that Omnient Labs "was started as an ISO accredited lab to do advanced lab testing for Nootropics Depot" and now sells testing to other brands as well, and that the company's owner built its contract manufacturer himself. The COA we read gives Omnient's address as Suite 105 at 8370 S Kyrene Road in Tempe; the retailer's own structured data puts it at Suite 107 of the same building. The accreditation is real and the data is far more than most sellers publish. It is still an in-house arrangement being described with the words "third party".

How much does it cost?

$29.99 for 30 capsules of 250 mg, $49.99 for 90 and $159.99 for 365 — a month, three months and a year at the suggested one a day. Per gram of NMN that is about $4.00, $2.22 and $1.75, so the entry size is the expensive way to buy it.

Does NMN really bypass the stomach via a dedicated transporter?

That is a mouse result stated as a human one. The page describes NMN absorbing through the small intestine via "its dedicated Slc12a8 transporter". Slc12a8 was identified as an NMN transporter by Grozio and colleagues in Nature Metabolism in 2019, and we read the abstract in September 2026: the gene is highly expressed in the mouse small intestine, knocking it down abolishes NMN uptake in cells and in mice, and losing it lowers NAD⁺ in the mouse jejunum and ileum. Careful work, and not a description of what happens after you swallow a capsule.

Is NMN "clinically validated anti-aging"?

No. Randomized human trials consistently show that oral NMN raises blood NAD⁺, and they show it safely across doses up to 900 mg a day. What they have not shown is the thing the phrase implies. The endpoints these trials actually report are blood NAD concentration, a six-minute walking distance, insulin sensitivity in a specific patient group, sleep and fatigue questionnaires — not lifespan, not healthspan, and not aging itself. A badge that compresses all of that into "clinically validated anti-aging" is doing work the underlying papers do not support, which is a pity on a page that is otherwise unusually careful with its data.

Is Nootropics Depot expensive compared with other NAD⁺ precursor supplements providers?

Nootropics Depot publishes a starting figure of $29.99/mo. Across the 116 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Nootropics Depot below the median, toward the cheaper end. The other 33 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Nootropics Depot review

Lot-level proof, vertical lab

Signed per-batch certificates you can match to the bottle in your hand, from a lab the seller founded to test its own products.

Our verdict

This is the paperwork standard the rest of this category should be held to. Nootropics Depot publishes a certificate for each lot, tells you to find your lot number and open the matching one, and the document that opens is a real analytical report: 283 mg of NMN per capsule against a 250 mg specification, identity by FTIR, heavy metals by ICP-MS reported in parts per million, a named signatory and an accreditation number. Two things temper it. The laboratory was founded by this company to test this company's products, and the contract manufacturer was built by the same owner — both of which Nootropics Depot states on its own site. And the mechanism copy promotes a mouse finding into human physiology.

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At a glance

Category: NMN supplement
Format: Oral precursor
From: $29.99
Dose published: Yes
Prescription: Not required
Compounded: No
Updated: September 2026

What it is

A one-capsule-a-day NMN supplement at 250 mg a capsule, sold in 30, 90 and 365 count bottles, with the same molecule also available as loose powder and as enteric-coated tablets. Nootropics Depot is a Tempe, Arizona retailer that has sold ingredient-grade compounds since 2013 and built its reputation on publishing analytical data rather than marketing copy.

How it works

Retail. No prescriber, no intake, no membership. The distinguishing feature is the testing apparatus, and the company is candid about its shape: it states that Omnient Labs, which produces its certificates, "was started as an ISO accredited lab to do advanced lab testing for Nootropics Depot" and now serves other brands too, and that its contract manufacturer was built by Nootropics Depot's own owner after too many bad batches from third parties. The COA we opened gives the laboratory's address as 8370 S Kyrene Road Suite 105 in Tempe; the retailer's own page gives Suite 107 at the same address.

Pricing transparency

$29.99 for the 30-count bottle, which at one capsule a day is a month and 7.5 grams of NMN — about $4.00 per gram. The bigger bottles change that picture substantially: 90 capsules is $49.99, near $2.22 a gram, and 365 capsules is $159.99, near $1.75 a gram and a full year at the suggested dose. Buying the small bottle costs more than twice as much per gram as buying the large one, which is worth knowing before you use $29.99 as this seller's price. There is no compare-at price, no coupon on the page and no subscription requirement.

Branded vs compounded

A dietary supplement, not FDA-approved and not reviewed by the FDA for safety or efficacy before sale. The analytical disclosure is the strongest thing here, and it is worth being specific about what it shows: identity confirmed against a library standard by infrared spectroscopy at 99% match, assay by ultraviolet-visible spectroscopy at 283 mg per capsule against a floor of 250 mg, loss on drying at 1%, water activity at 0.37, and arsenic, cadmium, mercury and lead each measured by mass spectrometry and each an order of magnitude below the 0.5 ppm limit. That is a genuine report, not a graphic with tick marks on it. Against that sits the mechanism copy, which says NMN "bypasses the stomach's acidic environment and absorbs directly through the small intestine via its dedicated Slc12a8 transporter." The transporter was identified in mice.

Pros and watch-outs

What we like

Publishes a separate signed certificate for every lot, matched by the number on your bottle
Certificates carry measured values — assay, identity, moisture, water activity and four heavy metals in ppm
The assay reports 283 mg per capsule against a 250 mg specification, so the overage is disclosed rather than rounded away
Names the testing laboratory, its accreditation body and its accreditation number
States plainly on its own site that the lab and the manufacturer are connected to it
The 365-capsule bottle at $159.99 is near $1.75 a gram, a year of a 250 mg daily dose bought at once

Watch-outs

The "third party" lab was founded by this company to test this company's products, by its own account
The contract manufacturer was built by the same owner, so the supply chain is vertical end to end
States a mouse transporter finding as an established route of human absorption
Carries a "Clinically Validated Anti-Aging" badge, which the endpoints of the published NMN trials do not support
About $4.00 per gram at the 30-count size, above several plainer sellers

Best for

Somebody who wants to read the analysis for the exact bottle they are holding, and who can weigh a disclosed conflict of interest instead of needing there to be none.

Who should look elsewhere

Anyone who reads "third-party tested" as meaning arm's length, without checking what the arm is attached to. Here the answer is published; elsewhere it usually is not.

How Nootropics Depot compares

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Rachel Kim

Biochemistry & mechanism · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Nootropics Depot’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

What is on the certificate of analysis?: Numbers. We opened the batch NMNC2CS1042425 certificate in September 2026. It names the lot, the raw material batch, the production and report dates and a best-by date of April 2028. Identity was confirmed by infrared spectroscopy at a 99% match to the library standard against a 95% specification. The assay, by ultraviolet-visible spectroscopy, reports 283 mg of nicotinamide mononucleotide per capsule against a specification of at least 250 mg. Loss on drying was 1%, water activity 0.37, and arsenic, cadmium, mercury and lead were each measured by ICP-MS well under the 0.5 ppm limit. It is signed by a named quality liaison and carries an ILAC-MRA mark and a PJLA accreditation number.
Is Omnient Labs independent?: Not in the sense most people mean, and Nootropics Depot says so itself. Its own page about its testing partners states that Omnient Labs "was started as an ISO accredited lab to do advanced lab testing for Nootropics Depot" and now sells testing to other brands as well, and that the company's owner built its contract manufacturer himself. The COA we read gives Omnient's address as Suite 105 at 8370 S Kyrene Road in Tempe; the retailer's own structured data puts it at Suite 107 of the same building. The accreditation is real and the data is far more than most sellers publish. It is still an in-house arrangement being described with the words "third party".
How much does it cost?: $29.99 for 30 capsules of 250 mg, $49.99 for 90 and $159.99 for 365 — a month, three months and a year at the suggested one a day. Per gram of NMN that is about $4.00, $2.22 and $1.75, so the entry size is the expensive way to buy it.
Does NMN really bypass the stomach via a dedicated transporter?: That is a mouse result stated as a human one. The page describes NMN absorbing through the small intestine via "its dedicated Slc12a8 transporter". Slc12a8 was identified as an NMN transporter by Grozio and colleagues in Nature Metabolism in 2019, and we read the abstract in September 2026: the gene is highly expressed in the mouse small intestine, knocking it down abolishes NMN uptake in cells and in mice, and losing it lowers NAD⁺ in the mouse jejunum and ileum. Careful work, and not a description of what happens after you swallow a capsule.
Is NMN "clinically validated anti-aging"?: No. Randomized human trials consistently show that oral NMN raises blood NAD⁺, and they show it safely across doses up to 900 mg a day. What they have not shown is the thing the phrase implies. The endpoints these trials actually report are blood NAD concentration, a six-minute walking distance, insulin sensitivity in a specific patient group, sleep and fatigue questionnaires — not lifespan, not healthspan, and not aging itself. A badge that compresses all of that into "clinically validated anti-aging" is doing work the underlying papers do not support, which is a pity on a page that is otherwise unusually careful with its data.
Is Nootropics Depot expensive compared with other NAD⁺ precursor supplements providers?: Nootropics Depot publishes a starting figure of $29.99/mo. Across the 116 NAD⁺ precursor supplements providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Nootropics Depot below the median, toward the cheaper end. The other 33 NAD⁺ precursor supplements providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

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