Is Rylo's NAD⁺ $183 or $219 a month?

Both, depending on the tier. $219 is the month-to-month rate on their NAD⁺ plan selector. The $183 is what the three-month plan works out to — the page states it as "$183/mo billed $549 every 3 months", so you pay $549 up front. We list $219 because that is the price with no commitment attached.

How much NAD⁺ do you get?

They publish the strength — "Ours is compounded at 100mg/mL for subcutaneous injection" — but not the volume you receive or the dosing schedule, so the milligrams per month are not established. That is still more than most sellers publish, and less than Neo Soma (100 mg a day, three days a week) or System Labs (1000 mg), where the arithmetic can be finished.

Do they admit injectable NAD⁺ is unproven?

Yes, more plainly than anyone else we have read. Their NAD⁺ disclaimer says the therapy "is considered experimental" and that "Clinical evidence for NAD+ injection therapy in humans remains limited", and their FAQ states that most published research has studied oral precursors — NMN and NR — rather than injectable NAD⁺. That is the accurate summary of the evidence, and it is unusual to find it on the page selling the injection.

Who actually fills the prescription?

They name it: "Prescriptions are filled by VialsRX, 6220 Westpark Dr, Houston, TX 77057", and clinical care is provided through Lone Star Virtual Health PLLC. That Houston address is the same one Vytora Health lists for its pharmacy partner "Vials Pharmacy", which is a useful reminder that two brands at different prices can be dispensing from the same facility.

Why review a provider you earn nothing from?

We hold no affiliate relationship with Rylo and earn nothing if you start care there. It is listed because it sells NAD⁺ at a published price. In this case it is also the review we would point a reader to first if they wanted to understand what the evidence for this category actually is, because the seller wrote it down.

Is Rylo Health legit?

Rylo Health is an NAD⁺ injection providers service. Its stated availability: All 50 states. It displays a LegitScript certification claim, which we record as a claim and not as a verified fact: LegitScript's public checker is gated and returns the same page for any domain put into it, so no one can reproduce a check from it. What our record does not establish: which medications it dispenses, whether it bills insurance and how its intake works. Ask for those in writing before you pay.

Is Rylo Health expensive compared with other NAD⁺ injection providers providers?

Rylo Health publishes a starting figure of $219/mo. Across the 116 NAD⁺ injection providers providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Rylo Health above the median. The other 33 NAD⁺ injection providers providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Rylo Health review

Calls it experimental

Names its pharmacy and its medical group, and publishes a strength. Then tells you in its own words that injectable NAD⁺ is experimental, and that the research is on oral precursors instead.

Our verdict

On disclosure Rylo is hard to fault. Its NAD⁺ page states "Compounded NAD+ is not FDA-approved. NAD+ injection therapy is considered experimental... Clinical evidence for NAD+ injection therapy in humans remains limited", and its FAQ adds the sentence the rest of the category avoids: "Most published research on NAD+ supplementation has studied oral precursors (NMN and NR), not injectable NAD+ directly." That is our own editorial position, printed by a seller against its own interest. The price needs reading, though. The $183 advertised across the site is the three-month prepay. Month to month you pay $219.

Disclosure: NAD Picks is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

Check availability →

At a glance

Category: NAD⁺ injections
Format: Injection
From: $219/mo
Dose published: Yes
Prescription: Required
Compounded: Yes — not FDA-approved
Pharmacy: Named
Labs: Not stated
Availability: All 50 states
LegitScript: Claimed by provider
Updated: September 2026

What it is

A cash-pay telehealth service selling compounded GLP-1s, NAD⁺, sermorelin, glutathione and a topical GHK-Cu cream, organized into weight, longevity and skin. NAD⁺ sits in longevity beside sermorelin.

How it works

Online intake, physician review the same day, medication shipped. Two things they name that almost nobody names: the clinical entity — "Clinical care is provided by Lone Star Virtual Health PLLC through licensed physicians in all 50 states, subject to state licensure" — and the dispensing pharmacy, "VialsRX, 6220 Westpark Dr, Houston, TX 77057", with a phone number. They also state no contracts, no cancellation fees and no membership fee, and that your current month's shipment ships before a cancellation takes effect.

Pricing transparency

Read the tier. The homepage, the product menu and the category page all advertise NAD⁺ "From $183/month", and the same line spells out what that is: "$183/mo billed $549 every 3 months". The month-to-month rate on the NAD⁺ page's own plan selector is $219. We record $219, because that is the price with no commitment attached, which puts Rylo level with Obu Health, a little above Yucca at $215, and below The Edit at $249. The prepay at $183 is genuinely cheaper if you are certain you want three months, which is a harder thing to be certain of for a therapy the seller itself calls experimental. They publish a strength — 100 mg/mL — but not how many milliliters you receive, so the price still cannot be reduced to a cost per milligram.

Branded vs compounded

Compounded NAD⁺, stated four different ways. The product name in their own data is "compounded NAD+". The footer says "Compounded by licensed US pharmacies" and elsewhere "Rylo's medications are compounded by licensed 503A compounding pharmacies against a valid prescription — that is, prepared to order rather than manufactured in batches. Compounded medications are not FDA-approved drug products, while brand-name versions are." The NAD⁺ disclaimer adds that the therapy "is considered experimental" and that "Clinical evidence for NAD+ injection therapy in humans remains limited". Their side-effect answer even cites the right study honestly: "A 2019 pilot study in elderly adults found that NAD+ infusions were well-tolerated with no serious adverse events. However, large-scale safety data are limited."

Pros and watch-outs

What we like

States in its own words that injectable NAD⁺ is experimental and that human evidence remains limited
Says most published NAD⁺ research is on oral precursors (NMN and NR) rather than injectable NAD⁺ — which a buyer should know
Names the dispensing pharmacy with a street address and phone number, and names the medical group providing clinical care
Publishes a strength, 100 mg/mL, which most sellers will not do
No contracts, no cancellation fees, no membership fee, and both price tiers shown side by side on the product page
Available in all 50 states, with the state-licensure caveat stated rather than hidden

Watch-outs

The $183 shown in the nav, on the homepage and on the category page is the three-month prepay; month to month is $219
$219 is upper-middle for this category — CoreAge is $93 and System Labs $149 for the same format
100 mg/mL is a concentration, not a dose: without a volume you still cannot work out what you receive per month
The candor cuts both ways — by their own account you are buying a therapy they describe as experimental

Best for

A reader who wants to know exactly what they are buying, from whom, and on what evidence. Few sellers name the pharmacy, the medical group and the limits of the research on the same site.

Who should look elsewhere

Anyone shopping the bottom of the market, or anyone who would sign up expecting the $183 headline to be what lands on their card each month.

How Rylo Health compares

A few alternatives worth a look, depending on what you’re optimizing for.

Care Bare Rx
Anyone who wants the price up front
See Care Bare Rx →
Breeze Meds
The lowest listed injection price
See Breeze Meds →
CoreAge Rx
The lowest published NAD⁺ price
See CoreAge Rx →

Compare all providers side by side →

More NAD⁺ injection providers reviews: Sprout HealthYourHealthRxYourEraNeo Soma HealthcareVytora HealthArc-1

Laura Bennett

Evidence & trials · Reviewed and last verified September 2026

How we assessed this. This review reflects NAD Picks’s own read of Rylo Health’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

Is Rylo's NAD⁺ $183 or $219 a month?: Both, depending on the tier. $219 is the month-to-month rate on their NAD⁺ plan selector. The $183 is what the three-month plan works out to — the page states it as "$183/mo billed $549 every 3 months", so you pay $549 up front. We list $219 because that is the price with no commitment attached.
How much NAD⁺ do you get?: They publish the strength — "Ours is compounded at 100mg/mL for subcutaneous injection" — but not the volume you receive or the dosing schedule, so the milligrams per month are not established. That is still more than most sellers publish, and less than Neo Soma (100 mg a day, three days a week) or System Labs (1000 mg), where the arithmetic can be finished.
Do they admit injectable NAD⁺ is unproven?: Yes, more plainly than anyone else we have read. Their NAD⁺ disclaimer says the therapy "is considered experimental" and that "Clinical evidence for NAD+ injection therapy in humans remains limited", and their FAQ states that most published research has studied oral precursors — NMN and NR — rather than injectable NAD⁺. That is the accurate summary of the evidence, and it is unusual to find it on the page selling the injection.
Who actually fills the prescription?: They name it: "Prescriptions are filled by VialsRX, 6220 Westpark Dr, Houston, TX 77057", and clinical care is provided through Lone Star Virtual Health PLLC. That Houston address is the same one Vytora Health lists for its pharmacy partner "Vials Pharmacy", which is a useful reminder that two brands at different prices can be dispensing from the same facility.
Why review a provider you earn nothing from?: We hold no affiliate relationship with Rylo and earn nothing if you start care there. It is listed because it sells NAD⁺ at a published price. In this case it is also the review we would point a reader to first if they wanted to understand what the evidence for this category actually is, because the seller wrote it down.
Is Rylo Health legit?: Rylo Health is an NAD⁺ injection providers service. Its stated availability: All 50 states. It displays a LegitScript certification claim, which we record as a claim and not as a verified fact: LegitScript's public checker is gated and returns the same page for any domain put into it, so no one can reproduce a check from it. What our record does not establish: which medications it dispenses, whether it bills insurance and how its intake works. Ask for those in writing before you pay.
Is Rylo Health expensive compared with other NAD⁺ injection providers providers?: Rylo Health publishes a starting figure of $219/mo. Across the 116 NAD⁺ injection providers providers we review that publish a single monthly figure, those run $17.97 to $799 with a median of $175, which puts Rylo Health above the median. The other 33 NAD⁺ injection providers providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every NAD⁺ injection provider.