NAD⁺ injection subscriptions run from about $93 to about $249 a month among the providers we have verified, and an in-home IV session runs $749 to $799. Those are the headline numbers, and on their own they will not tell you which is expensive.
The figure that does is cost per milligram, and almost nobody publishes the milligrams. That is the whole story of pricing in this category: a 2.7-fold spread between the cheapest and dearest monthly plans, with no way to know whether the cheapest is a bargain or simply a smaller vial.
The prices we can actually convert
Four sellers publish both a price and a quantity, which makes them the only points on the map with a scale attached:
- System Labs — $149 a month for a stated 1000 mg supply, about 15 cents a milligram.
- iThriveMD — $249 a month for a stated 1000 mg, around 25 cents a milligram.
- Eden — $186 for a 500 mg vial, roughly 37 cents a milligram.
- The IV Doc — $799 a session for a stated 250 mg, about $3.20 a milligram.
Line the first and last up and the finding is stark: the IV route costs roughly 13 to 21 times more per milligram than the injection sellers that publish a dose. Same molecule, same lack of controlled outcome trials, an order of magnitude apart on price. The infusion versus injection comparison is where that gap is worked through in full.
What the price hides
The intro month. Several programs advertise a first month well below the standing rate. Our roster records the standing rate, not the promotion, because that is what you will pay in month two — Eden’s $186 rather than the intro figure, for example.
The annual prepay. A monthly figure quoted against a twelve-month commitment is not the same product as a month-to-month one, and the difference frequently exceeds the difference between two competing brands.
The consultation and shipping. Some prices include the clinician visit and delivery; some do not. That gap is often $50 to $100 on the first month and is rarely on the pricing page.
The session count. For IV, this is the big one. A protocol is almost never one infusion, and the number of sessions is almost never published — so the annual cost of a drip program cannot be computed from the seller’s own page. Our annual cost tool exists to make you enter the number and see the total.
Where the money goes furthest
Oral precursors, by a wide margin, and it is not close. A Tru Niagensubscription is a fraction of any injection plan, and it is the format with randomized human trials behind its central claim. An eight-week randomized, placebo-controlled trial of nicotinamide riboside at 100, 300 and 1,000 mg raised whole blood NAD⁺ by 22%, 51% and 142% within two weeks [1], with no significant difference in adverse events against placebo.
Meanwhile a systematic review published in early 2026 searched human and rodent intervention studies of NAD-related compounds from January 2010 to October 2025, identified 113 eligible studies including 33 human intervention studies (28 randomized), and reported that no eligible outcomes trial evaluated intravenous or intramuscular NAD⁺ itself for anti-aging or wellness indications [2]. You are paying the most for the format with the least behind it.
None of which means an injection is a bad purchase. It means the premium is buying convenience, a prescription relationship and a delivery route — not a better-evidenced result — and that is a reasonable thing to buy as long as you know that is what you are buying.
How to shop this properly
Three steps, in this order.
One. Get the milligram figure in writing, with its basis — per injection, per vial or per month. Without it no comparison is possible, and asking for it is the most useful thing you can do before paying.
Two. Convert to cost per milligram. Our cost calculator does the arithmetic, and the price comparison lines up every seller we have verified with the unit kept attached to each number, so a session never gets read as a month.
Three. Check the standing rate, not the intro rate, and the twelve-month total rather than the first invoice. Our cheapest NAD⁺ therapy board ranks on what you actually end up paying, and the injection board carries the full roster with each provider’s published figure or, where there is none, the fact that there is none.
One last thing worth saying plainly: everything injectable here is compounded, which means it is not FDA-approved and is not reviewed by the FDA for safety, efficacy or quality before it is dispensed. Cost per milligram tells you about value. It does not tell you about quality, and no price in this category does.